Currently, there are no reliable clinical methods to predict the onset of spontaneous preterm birth (PTB) or preeclampsia (PE), both of which can lead to medically indicated preterm delivery. This presentation will explore emerging strategies for the prediction of PTB and PE, with a particular focus on the application of multiomics technologies. In addition, potential preventive and therapeutic interventions aimed at reducing the incidence and severity of PTB and PE will be examined.

This activity will review methodology and outcomes from platelet transfusion clinical trials for preterm infants. At the conclusion of the activity, learners will critically evaluate transfusion thresholds in their own unit to determine if a change in practice is merited and if so, implement at least one strategy, new technique(s), or intervention(s) to assist in clinical decision-making.

The monthly Obstetrics Grand Rounds Series will present topics on diagnosis and management of normal and complicated pregnancy, including routine and advanced obstetrical ultrasound. The series aims to review evidence-based standards of care and to provide contemporary, state-of-the art updates on topics where new information is available. At the conclusion of the activity, learners will implement at least one strategy, new technique(s), or intervention(s) to identify specific findings of diseas...

Despite advancements in neonatal care, initial respiratory management strategies for infants born at the limits of viability remain a significant challenge. Among those born at 24 to 25 weeks gestation, respiratory failure continues to account for approximately 50–60% of all deaths. This presentation will focus on innovative, evidence-based strategies to optimize the early use of high-frequency jet ventilation (HFJV) as a first-line respiratory modality in infants born during the canalicular sta...

The monthly Obstetrics Grand Rounds Series will present topics on diagnosis and management of normal and complicated pregnancy, including routine and advanced obstetrical ultrasound. The series aims to review evidence-based standards of care and to provide contemporary, state-of-the art updates on topics where new information is available. At the conclusion of the activity, learners will implement at least one strategy, new technique(s), or intervention(s) to identify specific findings of diseas...

There is currently a significant gap in research and clinical evidence regarding the benefit/risk ratio of administering moderate dose postnatal corticosteroid therapy in very preterm infants at high risk of bronchopulmonary dysplasia (BPD) between 7-21 days of age. Clinicians often mistakenly believe that any dose higher than the lowest (e.g., DART) of postnatal steroids is harmful to the developing brain and neurodevelopment. However, the disease we are treating, BPD, is more detrimental. Ther...

The monthly Obstetrics Grand Rounds Series will present topics on diagnosis and management of normal and complicated pregnancy, including routine and advanced obstetrical ultrasound. The series aims to review evidence-based standards of care and to provide contemporary, state-of-the art updates on topics where new information is available. At the conclusion of the activity, learners will implement at least one strategy, new technique(s), or intervention(s) to identify specific findings of diseas...

Continuous positive airway pressure (CPAP) practice and duration varies widely among neonatal intensive care units. This presentation will review the optimal length of time a stable preterm infant should be maintained on CPAP to promote lung growth and development. At the conclusion of the activity, learners will implement at least one strategy, new technique(s), or intervention(s) to identify when extended CPAP is indicated.

The monthly Obstetrics Grand Rounds Series will present topics on diagnosis and management of normal and complicated pregnancy, including routine and advanced obstetrical ultrasound. The series aims to review evidence-based standards of care and to provide contemporary, state-of-the art updates on topics where new information is available. At the conclusion of the activity, learners will implement at least one strategy, new technique(s), or intervention(s) to identify specific findings of diseas...

Neonatologists have little training or experience in evaluating placental pathology results that may be relevant for newborn care. At the conclusion of the activity, learners will implement at least one strategy, new technique(s), or intervention(s) to identify when a placental pathologic exam is indicated and how to interpret key findings.